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LucenceINSIGHT™ is a multi-cancer early detection (MCED) next generation sequencing test that screens for the signal of up to 50 cancers in one simple blood draw.

The test uses Lucence’s amplicon-based mirror barcoding technology to detect circulating tumor and viral DNA. It then predicts tumor location with machine learning.

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LucenceINSIGHT™ Screens For Cancer With High Accuracy.

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Evidence


  • LucenceINSIGHT™ reported 100% positive predictive value (PPV) from a prospective real-world cohort of 264 asymptomatic individuals in 2023.3
  • A performance of 81% sensitivity and 99% specificity was reported from a retrospective cohort of 601 patient samples in 2024.1
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Case Study: Colorectal Cancer3


  • Patient: 60+ year old asymptomatic Southeast Asian male
  • Detected mutation: RHOA G62E at 0.4% VAF
  • Diagnostic workup: PET-CT
  • Final Diagnosis: Stage III colorectal cancer
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Focal uptake detected in right ascending colon

  • Patient: 60+ year old asymptomatic Southeast Asian male
  • Detected mutation: RHOA G62E at 0.4% VAF
  • Diagnostic workup: PET-CT
  • Final Diagnosis: Stage III colorectal cancer

Focal uptake detected in right ascending colon

Frequently Asked Questions


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References

  1. Poh, J. et al. J. Clin. Oncol. 2024; 42(16): e15042.
  2. Croswell, J. et al. Ann. Fam. Med. 2009; 7(3): 212–222.
  3. Tucker, S. et al. Ann. Oncol. 2023; 34: S1625-S1626.
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