Cancer is a genetic disease caused by changes in our genes. Genes are the instructions that tell our bodies how to grow and work. Sometimes, changes or alterations in our genes can cause cells to grow and multiply in an uncontrolled way, leading to cancer.

Cancer can start in many different parts of the body, like the lungs, colon or stomach. As tumor cells grow, they shed fragments of DNA and RNA into the blood known as circulating tumor DNA (ctDNA) and circulating tumor RNA (ctRNA). These ctDNA and ctRNA contain evidence of gene alterations and their profiles are often characteristic of the organ from which they originated.

Viruses such as Epstein-Barr virus (EBV) and Human Papilloma Virus (HPV) are known to be associated with cancer proliferation. After the viral infection, parts of the viral DNA integrate with the individual’s DNA, making changes to the instructions on cell growth, and paving the potential onset of uncontrolled growth in the body.

LucenceINSIGHT^® should be used in addition to routine screening tests recommended by a doctor.

Please contact your healthcare provider to order a LucenceINSIGHT^® test.

If your doctor does not offer LucenceINSIGHT^® at their practice, kindly reach out to us and we will make the introductions.

Annual screening is recommended. 

Your healthcare provider will determine an appropriate screening interval based on your existing medical risks.

LucenceINSIGHT^® detected alterations associated with cancer.

Some individuals with cancer-associated alterations may not have cancer, but instead clonal hematopoiesis.

This result is not a diagnosis. Further confirmatory diagnostic testing is recommended as guided by your healthcare provider.

False-positive and false-negative results do occur. False negatives can occur due to biological reasons such as low DNA shedding or small tumor size. If further confirmatory testing does not confirm cancer, it could mean that cancer is not present or that confirmatory testing was insufficient to detect the cancer signal.